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2016 Publication

  1. MS Wen, KC Chang, TH Lee, YF Chen, KC Hung, YJ Chang, CW Liou, JJ Chen, CH Chang, CY Wang, JS Jeng, HP Chuang, YT Chen, CH Chen, JY Wu, YT Chen & MT Michael Lee. Pharmacogenetic dosing of warfarin in the Han-Chinese population: a randomized trial. Future Medicine. 2017 Jan. (IF: 2.710)

  2. NH Wang, SJ Chen, CF Yang, HW Chen, HP Chuang, YH Lu, CH Chen, JY Wu, DM Niu, YT Chen. Homozygosity Mapping and Whole-Genome Sequencing Links a Missense Mutation in POMGNT1 to Autosomal Recessive Retinitis Pigmentosa. Invest Ophthalmol Vis Sci. 2016 Jul. (IF:3.427)

  3. TP Chuang, JY Wang, SW Jao, CC Wu, JH Chen, KH Hsiao, CY Lin, SH Chen, SY Su, YJ Chen, YT Chen, DC Wu, LH Li. Over-expression of AURKA, SKA3 and DSN1 contributes to colorectal adenoma to carcinoma progression. Oncotarget. 2016 Jun. (IF: 5.008)

  4. IW Song, CC Sung, CH Chen, CJ Cheng, SS Yang, YC Chou, JH Yang, YT Chen, JY Wu, SH Lin. Novel susceptibility gene for nonfamilial hypokalemic periodic paralysis. Neurology. 2016 Mar. (IF: 8.286)

  5. TH Lee, TM Ko, CH Chen, MT Lee, YJ Chang, CH Chang, KL Huang, TY Chang, JD Lee, KC Chang, JT Yang, MS Wen, CY Wang, YT Chen, CS Hsieh, SY Chou, YM Liu, HW Chen, HT Liao, CW Wang, SP Chen, LS Lu, YT Chen, JY Wu. Identification of PTCSC3 as a Novel Locus for Large-Vessel Ischemic Stroke: A Genome-Wide Association Study. Journal of American Heart Association. 2016 Mar. (IF: 5.117)

  6. TM Ko, CS Wong, JY Wu, YT Chen. Pharmacogenomics for Personalized Pain Medicine. ACTA Acta Anaesthesiologica Taiwanica. 2016 Feb.

2015 Publication

  1. TM Ko, CY Tsai, SY Chen, KS Chen, KH Yu, CS Chu, CM Huang, CR Wang, CT Weng, CL Yu, SC Hsieh, JC Tsai, WT Lai, WC Tsai, GD Yin, TT Ou, KH Cheng, JH Yen, TL Liou, TH Lin, DY Chen, PJ Hsiao, MY Weng, YM Chen, CH Chen, MF Liu, HW Yen, JJ Lee, MC Kuo, CC Wu, SY Hung, SF Luo, YH Yang, HP Chuang, YC Chou, HT Liao, CW Wang, CL Huang, CS Chang, MT Lee, P Chen, CS Wong, CH Chen, JY Wu, YT Chen, CY Shen; Taiwan Allopurinol-SCAR Consortium. Use of HLA-B*58:01 genotyping to prevent allopurinol induced severe cutaneous adverse reactions in Taiwan: national prospective cohort study. British Medical Journal. 2015 Sep 23;351:h4848. (IF: 17.445)

  2. TM Ko, YT Chen, JY Wu. Precision Medicine for Kawasaki Disease. Medical Research Archives. 2015 Aug. (IF: 11.470)

  3. PL Chen, SR Shih, PW Wang, YC Lin, CC Chu, JH Lin, SC Chen, CC Chang, TS Huang, KS Tsai, FY Tseng, CY Wang, JY Lu, WY Chiu, CC Chang, YH Chen, YT Chen, CS Fann, WS Yang, TC Chang. Genetic determinants of antithyroid drug-induced agranulocytosis by human leukocyte antigen genotyping and genome-wide association study. Nat Commun. 2015 Jul 7;6:7633. (IF: 11.470)

  4. CH Lin, JK Chen, TM Ko, CY Wei, JY Wu, WH Chung, SY Chen, YD Liao, SI Hung, YT Chen. Immunologic basis for allopurinol-induced severe cutaneous adverse reactions: HLA-B*58:01-restricted activation of drug-specific T cells and molecular interaction. Journal of Allergy and Clinical Immunology. 2015 Apr;135(4):1063-5.e5. (IF: 11.476)

  5. TM Ko, HC Kuo, JS Chang, SP Chen, YM Liu, HW Chen, FJ Tsai, YC Lee, CH Chen, JY Wu, YT Chen. CXCL10/IP-10 is a Biomarker and Mediator for Kawasaki Disease. Circulation Research 2015 Feb. (IF: 11.089)

2014 Publication

  1. SW Chang, CSJ Fann, WH Su, YC Wang, CC Weng, CJ Yu, CL Hsu, AR Hsieh, RN Chien, CM Chu and DI Tai. A Genome-Wide Association Study on Chronic HBV Infection and Its Clinical Progression in Male Han-Taiwanese. PLoS ONE 2014 Jun; 9(6):e99724. (IF: 3.534)
  1. DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium, South Asian Type 2 Diabetes (SAT2D) Consortium, Mexican American Type 2 Diabetes (MAT2D) Consortium & Type 2 Diabetes Genetic Exploration by Next-generation sequencing in multi-Ethnic Samples (T2D-GENES) Consortium. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nature Genetics 2014 Mar; 46(3):234-44. (IF: 29.648)
  1. B Xi, F Takeuchi, A Meirhaeghe, N Kato, JC Chambers, AP Morris, YS Cho, W Zhang , KL Mohlke, JS Kooner, XO Shu, H Pan, ES Tai, H Pan, JY Wu, D Zhou, GR Chandak, DIAGRAM Consortium, AGEN-T2D Consortium and SAT2D Consortium. Associations of genetic variants in/near body mass index-associated genes with type 2 diabetes: a systematic meta-analysis. Clinical Endocrinology 2014 Feb; doi: 10.1111/cen.12428. (IF: 3.353)
  1. DS Lin, TP Chuang, MF Chiang, CS Ho, CD Hsiao, YW Huang, TY Wu, JY Wu, YT Chen, TC Chen, LH Li. De novo MECP2 duplication derived from paternal germ line result in dysmorphism and developmental delay. Gene 2014 Jan; 533(1):78–85. (IF: 2.196)
  1. CH Chen, CS Lee, MT Lee, WC Ouyang, CC Chen, MY Chong, JY Wu, HK Tan, YC Lee, LJ Chuo, NY Chiu, HY Tsang, TJ Chang, FW Lung, CH Chiu, CH Chang, YS Chen, YM Hou, CC Chen, TJ Lai, CL Tung, CY Chen, HY Lane, TP Su, J Feng, JJ Lin, CJ Chang, PR Teng, CY Liu, CK Chen, IC Liu, JJ Chen, T Lu, CC Fan, CK Wu, CF Li, KH Wang, LS Wu, HL Peng, CP Chang, LS Lu, YT Chen, AT Cheng; for the Taiwan Bipolar Consortium. Variant GADL1 and Response to Lithium Therapy in Bipolar I Disorder. The New England Journal of Medicine 2014 Jan; 370(2):119-28. (IF: 47.05)
  1. R Villegas, SM Williams, YT Gao, J Long, J Shi, H Cai, H Li, CC Chen, ES Tai, AGEN-T2D Consortium, F Hu, Q Cai1, W Zheng, XO Shu. Genetic variation in the peroxisome proliferator-activated receptor (PPAR) and peroxisome proliferator-activated receptor gamma co-activator 1 (PGC1) gene families and type 2 diabetes. Annals of Human Genetics 2014 Jan; 78(1):23-32. (IF: 1.926)

2013 Publication

  1. HC Liao, YH Huang, YJ Chen, SM Kao, HY Lin, CK Huang, HC Liu, TR Hsu, SP Lin, CF Yang, CS Fann, PC Chiu, KS Hsieh, YC Fu, YY Ke, CY Lin, FJ Tsai, CH Wang, MC Chao, WC Yu, CC Chiang, DM Niu. Plasma globotriaosylsphingosine (lysoGb3) could be a biomarker for Fabry disease with a Chinese hotspot late-onset mutation (IVS4+919G>A). Clin Chim Acta 2013 Nov 15;426:114-20. (IF: 2.764)
     
  2. CH Chou, CC Wu, IW Song, HP Chuang,LS Lu, JH Chang, SY Kuo, CH Lee, JY Wu, YT Chen, VB Kraus and MT Lee, Genome-wide expression profiles of subchondral bone in osteoarthritis. Arthritis Research & Therapy 2013 Nov, 15:R190 doi:10.1186/ar4380. (IF: 4.12)
     
  3. CJ Chang, HC Kuo, JS Chang, JK Lee, FJ Tsai, CC Khor, LC Chang, SP Chen, TM Ko, YM Liu, YJ Chen, YM Hong, GYg Jang, ML Hibberd, T Kuijpers, D Burgner, M Levin, J Burns, S Davila, International Kawasaki Disease Genetics Consortium, Korean Kawasaki Disease Genetics Consortium, Taiwan Kawasaki Disease Genetics Consortium, YT Chen, CH Chen, JY Wu & YCLee. Replication and meta-analysis of GWAS identified susceptibility loci in Kawasaki disease confirm the importance of B lymphoid tyrosine kinase (BLK) in disease susceptibility. PLoS ONE 2013 Aug; 8(8): e72037. (IF: 3.73)

2012 Publication

  1. CH Chou, CH Lee, LS Lu, IW Song, HP Chuang, SY Kuo, JY Wu, YT Chen, VB Kraus, CC Wu, MT Lee. Direct assessment of articular cartilage and underlying subchondral bone reveals a progressive gene expression change in human osteoarthritic knees. Osteoarthritis Cartilage 2012 Dec 5. pii: S1063-4584(12)01029-1. doi: 10.1016/j.joca.2012.11.016. (IF: 3.904)

  2. CY Wei, MT Michael Lee, YT Chen. Pharmacogenomics of adverse drug reactions: implementing personalized medicine. Human Molecular Genetics 2012 Oct 15;21(R1):R58-R65. Epub 2012 Aug 19. (IF: 7.692)

  3. Y Okada, X Sim, MJ Go, JY Wu, D Gu, F Takeuchi, A Takahashi, S Maeda, T Tsunoda, P Chen, SC Lim, TY Wong, J Liu, TL Young, T Aung, M Seielstad, YY Teo, YJ Kim, JY Lee, BG Han, D Kang, CH Chen, FJ Tsai, LC Chang, F SJ ann, H Mei, DC Rao, JE Hixson, S Chen, T Katsuya, M Isono, T Ogihara, JC Chambers, W Zhang, JS Kooner; KidneyGen Consortium; CKDGen Consortium, Albrecht E; GUGC consortium, K Yamamoto, M Kubo, Y Nakamura, N Kamatani, N Kato, J He, YT Chen, YS Cho, ES Tai, T Tanaka. Meta-analysis identifies multiple loci associated with kidney function–related traits in east Asian populations. Nature Genetics 2012 Jul 15;44(8):904-909. (IF: 36.377)

  4. TM Ko, YT Chen. T-cell receptor and carbamazepine-induced Stevens–Johnson syndrome and toxic epidermal necrolysis: understanding a hypersensitivity reaction. Expert Rev. Clin. Immunol 2012 Jul;8(5), 467–477. (IF: 2.072)

  5. YC Lee, HC Kuo, JS Chang, LY Chang, LM Huang, MR Chen, CD Liang, H Chi, FY Huang, ML Lee, YC Huang, B Hwang, NC Chiu, KP Hwang, PC Lee, LC Chang, YM Liu, YJ Chen, CH Chen, Taiwan Pediatric ID Alliance, YT Chen, FJ Tsai, JY Wu. Two new susceptibility loci for Kawasaki disease identified through genome-wide association analysis. Nature Genetics 2012 Mar doi:10.1038/ng.2227. (IF: 36.377)

2011 Publication

  1. YS Cho, CH Chen, C Hu, J Long, RT Hee Ong, X Sim, F Takeuchi, Y Wu, MJ Go, T Yamauchi, YC Chang, SH Kwak, RC Ma, K Yamamoto, LS Adai, T Aung, Q Cai, LC Chang, YT Chen, Y Gao, F B Hu, HL Kim, S Kim, YJ Kim, JJ Lee, NR Lee, Y Li, JJ Liu, W Lu, J Nakamura, E Nakashima, DP Ng, WT Tay, FJ Tsai, TY Wong, M Yokota, W Zheng, R Zhang, C Wang, WY So, K Ohnaka, H Ikegami, K Hara, YM Cho, NH Cho, TJ Chang, Y Bao, ÅK Hedman, AP Morris, MI McCarthy, DIAGRAM Consortium, MuTHER Consortium, R Takayanagi, KS Park, W Jia, LM Chuang, JC Chan, S Maeda, T Kadowaki, JY Lee, JY Wu, YY Teo, ES Tai, XO Shu, KL Mohlke, N Kato, BG Han, M Seielstad. Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. Nature Genetics 2011 Dec; 44(1):67-72. (IF: 35.532)

  2. CC Khor, S Davila, WB Breunis, YC Lee, C Shimizu, VJ Wright, RS Yeung, DE Tan, KS Sim, JJ Wang, TY Wong, J Pang, P Mitchell, R Cimaz, N Dahdah, YF Cheung, GY Huang, W Yang, IS Park, JK Lee, JY Wu, M Levin, JC Burns, D Burgner, TW Kuijpers, ML Hibberd; Hong Kong–Shanghai Kawasaki Disease Genetics Consortium, YL Lau, J Zhang, XJ Ma, F Liu, L Wu; Korean Kawasaki Disease Genetics Consortium, JJ Yoo, SJ Hong, KJ Kim, JJ Kim, YM Park, YM Hong, S Sohn, GY Jang, KS Ha, HK Nam, JH Byeon, SW Yun, MK Han, KY Lee, JY Hwang, JW Rhim, MS Song, HD Lee, DS Kim, JM Lee; Taiwan Kawasaki Disease Genetics Consortium, JS Chang, FJ Tsai, CD Liang, MR Chen, H Chi, NC Chiu, FY Huang, LY Chang, LM Huang, HC Kuo, KP Huang, ML Lee, B Hwang, YC Huang, PC Lee; International Kawasaki Disease Genetics Consortium, M Odam, FT Christiansen, C Witt, P Goldwater, N Curtis, P Palasanthiran, J Ziegler, M Nissen, C Nourse, IM Kuipers, JJ Ottenkamp, J Geissler, M Biezeveld, C Tacke, L Filippini, P Brogan, N Klein, V Shah, M Dillon, R Booy, D Shingadia, A Bose, T Mukasa, R Tulloh, C Michie; US Kawasaki Disease Genetics Consortium, JW Newburger, AL Baker, AH Rowley, ST Shulman, W Mason, M Takahashi, ME Melish, AH Tremoulet; Blue Mountains Eye Study, A Viswanathan, E Rochtchina, J Attia, R Scott, E Holliday, S Harrap. Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease. Nature Genetics 2011 Nov; 43(12):1241-6. (IF: 35.532)

  3. N Kato, F Takeuchi, Y Tabara, TN Kelly, MJ Go, X Sim, WT Tay, CH Chen, Y Zhang, K Yamamoto, T Katsuya, M Yokota, YJ Kim, RT Hee Ong, T Nabika, D Gu, LC Chang, Y Kokubo, W Huang, K Ohnaka, Y Yamori, E Nakashima, CE Jaquish, JY Lee, M Seielstad, M Isono, JE Hixson, YT Chen, T Miki, X Zhou, T Sugiyama, JP Jeon, JJ Liu, R Takayanagi, SS Kim, T Aung, YJ Sung, X Zhang, TY Wong, BG Han, S Kobayashi, T Ogihara, D Zhu, N Iwai, JY Wu, YY Teo, ES Tai, YS Cho, J He. Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians. Nature Genetics 2011 Jun; 43:531–538. (IF: 36.377)

  4. P Chen, JJ Lin, CS Lu, CT Ong, PF Hsieh, CC Yang, CT Tai, SL Wu, CH Lu, YC Hsu, HY Yu, LS Ro, CT Lu, CC Chu, JJ Tsai, YH Su, SH Lan, SF Sung, SY Lin, HP Chuang, LC Huang, YJ Chen, PJ Tsai, HT Liao, YH Lin, CH Chen, WH Chung, SI Hung, JY Wu, CF Chang, L Chen, YT Chen, CY Shen. Carbamazepine-Induced Toxic Effects and HLA-B*1502 Screening in Taiwan. The New England Journal of Medicine 2011 Mar; 364(12): 1126-1133. (IF: 47.05)

  5. FJ Tsai, YC Lee, JS Chang, LM Huang, FY Huang, NC Chiu, MR Chen, H Chi, YJ Lee, L Chang, YM Liu, HW Wang, CH Chen, YT Chen, JY Wu. Identification of Novel Susceptibility Loci for Kawasaki Disease in a Han Chinese Population by a Genome-Wide Association Study. PLoS ONE 2011 Feb; 6(2): e16853. (IF: 4.351)

2010 Publication

  1. SI Hung, WH Chung, ZS Liu, CH Chen, MS Hsih, RC Hui, CY Chu, YT Chen. Common risk allele in aromatic antiepileptic-drug induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese. Pharmacogenomics 2010; 11(3): 349-356. (IF: 3.551)

  2. NA Limdi, M Wadelius, L Cavallari, N Eriksson, DC Crawford, MTM Lee, CH Chen, A Motsinger-Reif, H Sagreiya, N Liu, AHB Wu, BF Gage, A Jorgensen, M Pirmohamed, JG Shin, G Suarez-Kurtz, SE Kimmel, JA Johnson, TE Klein and MJ Wagner on behalf of the IWPC. Warfarin Pharmacogenetics: A single VKORC1 polymorphism is predictive of dose across three racial groups. Blood 2010 May; 115(18):3827-3834. (IF: 10.132)

  3. MTM Lee, CH Chen, CS Lee, CC Chen, MY Chong, WC Ouyang, NY Chiu, LJ Chuo, CY Chen, HKL Tan, HY Lane, TJ Chang, CH Lin, SH Jou, YM Hou, J Feng, TJ Lai, CL Tung, TJ Chen, CJ Chang, FW Lung, CK Chen, IS Shiah, CY Liu, PR Teng, KH Chen, LJ Shen, CS Cheng, TP Chang, CF Li, CH Chou, CY Chen, KHT Wang, CSJ Fann, JY Wu, YT Chen, ATA Cheng. Genome-wide Association study of bipolar I disorder in the Han Chinese population. Molecular Psychiatry 2010 April; doi: 10.1038/mp.2010.43 (IF: 12.537)
  4. FJ Tsai, CF Yang, CC Chen, LM Chuang, CH Lu, CT Chang, TY Wang, RH Chen, CF Shiu, YM Liu, CC Chang, P Chen, CH Chen, CSJ Fann, YT Chen, JY Wu. A Genome-wide Association study identifies susceptibility variants for type 2 diabetes in Han Chinese. PLoS Genetics 2010; 6(2): e1000847. doi:10.1371/journal.pgen.1000847 (IF: 8.883)

  5. YC Lee, HY Huang, CJ Chang, CH Cheng, YT Chen. Mitochondrial GLUT10 facilitates dehydroascorbic acid import and protects cell against oxidative stress: mechanistic insight into arterial tortuosity syndrome. Human Molecular Genetics 2010; 19(19): 3721-3733. (IF: 7.386)

  6. HC Yang, HC Lin, MC Huang, LH Li, WH Pan, JY Wu, YT Chen. A new analysis tool for individual-level allele frequency for genomic studies. BMC Genomics 2010 Jul; 11:415. (IF: 3.759)

  7. CF Chang, LH Li, CH Wong, FJ Tsai, TC Chen, JY Wu, YT Chen, ACH Tsai. Identification of a submicroscopic 3.2 Mb chromosomal 16q12.2-13 deletion in a child with short stature, craniofacial malformation, hypoplastic ears by high density oligonucleotide array-a recognizable syndrome. American Journal of Medical Genetics Part A 2010 Sep;152A(9) : 2365-2371. (IF: 2.404)

  8. YC Lee, CJ Chang, Deeksha Bali3, YT Chen, YT Yan. Glycogen-branching enzyme deficiency leads to abnormal cardiac development: novel insights into glycogen storage disease IV. Human Molecular Genetics 2010; doi:10.1093/hmg/ddq4. (IF: 7.386)
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